Selection Signature Analysis for Important Economic Traits in Sheep (Ovis aries)

Background: Many genomic imprinting left during long-term selective evolution may drive the formation of important economical traits introduced and indigenous sheep breeds. Methods: In this study, OvineSNP50 BeadChip data breeds GMM DOR breed Sunit were downloaded from public databases. Selective sweep base on Pi Fst strategy initially screened for a number candidate genes that could explain genetic mechanism elucidated genetic-molecular mechanisms underlying differentiation growth development reproductive between Result: DOR_VS_GMM group, 32 identified. DOR_VS_SUN 26 GMM_VS_SUN 25 GO, KEGG enrichment analysis showed these are mainly involved in pathways muscle regulation. We speculate EHBP1, CSRP1, TNNI1, MBNL1, AADACL3, RDH13, TNNI3, BMP2, Wfdc8, PPP1CC2 MOV10L1 have deep marks genome domestication be responsible productive performance Merino sheep. These played an role selection three It is expected selected will provide some insights future germplasm mining foreign introductions.